E a strict up- or down- directionality. For instance, in cell glycolysis, we observed improved ALDOB, PGK1 and ALDH2 and decreased FBP1. However, our data has revealed many generally changed proteins which resulted from each male and female CYP2E1 knockout mice fed the dextrose diet plan. Within the major 10 up- and down-regulated proteins, six out on the ten up-regulated proteins (CKM, MB, MYLPF,